| Clofibrate | Caenorhabditis elegans | 16.2 | | | 23603800 |
| Cortexolone Maleate | Caenorhabditis elegans | 11.0 | | | 24134630 |
| Creatine | Mice | | 9.0 | | 17416441 |
| Curcumin | Caenorhabditis elegans | 45.0 | | | 21451522 |
| Curcumin | Drosophila melanogaster | 19.0 | | | 20645870 |
| Cyclosporin A | Caenorhabditis elegans | 15.0 | | | 24134630 |
| Cyproterone Acetate | Caenorhabditis elegans | 23.0 | | | 24134630 |
| Cysteamine | Mice | 45.0 | | | 11341102 |
| D-Chiro-Inositol | Drosophila melanogaster | | 16.7 | | 22843669 |
| D-Glucosamine | Mice | | | | 24714520 |
| D-Glucosamine | Human | | | | 22828954 |
| D-Pinitol | Drosophila melanogaster | 13.0 | | | 22843669 |
| Dafadine-A | Caenorhabditis elegans | 29.0 | | | 22057127 |
| Danazol | Caenorhabditis elegans | 13.0 | | | 24134630 |
| DAPH | Caenorhabditis elegans | 15.0 | | | 24134630 |
| Demeclocycline | Caenorhabditis elegans | 16.0 | | | 24134630 |
| Deprenyl | Rat | 15.0 | | | 8423709 |
| DHhP-6 | Caenorhabditis elegans | 21.7 | | | 23410029 |
| Diazaborine | Saccharomyces cerevisiae | | | | 18423200 |
| Dibromoacetic Acid | Caenorhabiditis elegans | 14.6 | | | 25556763 |
| Didanosine | Drosophila melanogaster | 5.0 | | | 7518199 |
| Dihydroergotamine Methanesulfonate | Caenorhabditis elegans | 34.0 | | | 24134630 |
| Dihydroergotamine Methanesulfonate | Caenorhabditis elegans | 24.0 | | | 24134630 |
| Dimethyl Formamide | Caenorhabditis elegans | 30.0 | | | 23313473 |
| Dimethyl Sulfoxide | Caenorhabditis elegans | 24.4 | | | 20828537 |
