Dihydroergotamine Methanesulfonate
CAS: 24730-10-7
Name:
Dihydroergotamine Methanesulfonate
Other names:
EINECS 246-434-6; Ergocristine, dihydro-, methanesulfonate; 9,10-Dihydroergocristine methanesulfonate
Dihydroergotamine Methanesulfonate Salt is a competitive serotonin antagonist and vasoconstrictor.
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- > 0.0
- oral LD50 [rat] mg/kg
- > 2643.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
+
Suppression of aging mechanisms
No dataRelation to biomarkers of Aging
Statistically significant positive effects on symptoms of cognitive dysfunction
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 34.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,33%
More info about experiment
Opposite effectNo
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 24.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,33%
More info about experiment
Opposite effectNo