Dihydroergotamine Methanesulfonate

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CAS: 24730-10-7

Name:

Dihydroergotamine Methanesulfonate

Other names:

EINECS 246-434-6; Ergocristine, dihydro-, methanesulfonate; 9,10-Dihydroergocristine methanesulfonate

Dihydroergotamine Methanesulfonate Salt is a competitive serotonin antagonist and vasoconstrictor.

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
> 0.0
oral LD50 [rat] mg/kg
> 2643.0
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

No data
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

Stress Resistance
+

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Statistically significant positive effects on symptoms of cognitive dysfunction

1606351

Relation to aging associated genes

No data available

Experimental conditions

S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50

Life Extension

Mean LS (%)
34.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

0,33%

More info about experiment

24134630
Opposite effectNo

Experimental conditions

S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50

Life Extension

Mean LS (%)
24.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

0,33%

More info about experiment

24134630
Opposite effectNo