Demeclocycline
CAS: 127-33-3
Name:
Demeclocycline
Other names:
Declomycin; DMCTC; Elkamicina; Demeclocycline HCL
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time. [PubChem]
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- > 2372.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Neuroprotective
Antibacterial
S4279
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
+
Suppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 16.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,33%
More info about experiment
Opposite effectNo