D-Chiro-Inositol

Imageshandler

CAS: 643-12-9

Name:

D-Chiro-Inositol

Other names:

DCI; myo-inositol; inositol; meso-Inositol; Scyllo-inositol; Muco-Inositol; i-Inositol; Allo-inositol; Myoinositol; epi-Inositol

An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction [MeSH].

Interactions

Description

UniProt ID

Protein: Maltase-glucoamylase, intestinal, Gene: MGAM
Protein: Glycosylphosphatidylinositol anchor attachment 1 protein, Gene: GPAA1
Protein: Citrate synthase, mitochondrial, Gene: CS
Protein: Trehalase, Gene: TREH

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Inflammation
Anti Cancer
+
Anti Diabetic
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

Anti Oxidant

Relation to biomarkers of Aging

Accelerated glucose disposal and sensitized insulin action

11900279

Relation to aging associated genes

TERT

Experimental conditions

Not available

Life Extension

Mean LS (%)
Median LS (%)
16.7
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

20 mkM

More info about experiment

22843669
Opposite effectNo