Cysteamine
CAS: 60-23-1
Name:
Cysteamine
Other names:
MEA; 2-Aminoethanethiol; CYSTEAMINE; Mercaptamine; Becaptan; Thioethanolamine; Cysteinamine; Mercamine; Decarboxycysteine; beta-Mercaptoethylamine
Cysteamine is a radiation-protective agent that oxidizes in air to form cystamine. It can be given intravenously or orally to treat radiation sickness. The bitartrate and hydrochloride salt forms are indicated for the treatment of neuropathic cystinosis in patients 6 years old and older. [PubChem]. Cysteamine is marketed under several brand names such as Cystaran™, Procysbi, and Cystagon®.
Interactions
Description
UniProt ID
Protein: Glutaminyl-peptide cyclotransferase, Gene: QPCT
Protein: Protein-glutamine gamma-glutamyltransferase 2, Gene: TGM2
Toxicity
- oral LD50 [mouse] mg/kg
- > 625.0
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Anti Inflammation
Anti Cancer
Anti Depressant
Neuroprotective
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
Anti Oxidant
Relation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelMice
SrainB/W mouse model of SLE
SexFemale
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 45.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
More info about experiment
Opposite effectNo