Trametinib

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CAS: 871700-17-3

Name:

Trametinib

Other names:

Trametinib; GSK1120212; GSK 1120212; JTP 74057; JTP-74057

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Inflammation
Anti Cancer
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Data not available

Relation to aging associated genes

No data available

Experimental conditions

Not available

Life Extension

Mean LS (%)
Median LS (%)
12.0
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

15.6 mM

Opposite effectNo

Experimental conditions

Not available

Life Extension

Mean LS (%)
Median LS (%)
8.0
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

1.56 mM

Opposite effectNo