Trametinib
CAS: 871700-17-3
Name:
Trametinib
Other names:
Trametinib; GSK1120212; GSK 1120212; JTP 74057; JTP-74057
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Model organism
ModelDrosophila melanogaster
SrainwDahomey
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- —
- Median LS (%)
- 12.0
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
15.6 mM
More info about experiment
Opposite effectNo
Model organism
ModelDrosophila melanogaster
SrainwDahomey
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- —
- Median LS (%)
- 8.0
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
1.56 mM
More info about experiment
Opposite effectNo