Α-Lipoic Acid
CAS: 62-46-4
Name:
Α-Lipoic Acid
Other names:
dl-Thioctic acid; alpha-Lipoic acid; 6,8-Thioctic acid; 6-Thioctic acid; lipoic acid; Biletan
α-lipoic acid is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism. It is also manufactured and is available as a dietary supplement in some countries where it is marketed as an antioxidant, and is available as a pharmaceutical drug in other countries [Wiki].
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Anti Inflammation
Anti Cancer
Anti Obesity
Neuroprotective
Cardioprotective
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Relation to biomarkers of Aging
Positively affecting oxidative stress, cognitive function, and cardiovascular function
Relation to aging associated genes
No data available
Model organism
ModelDrosophila melanogaster
SrainCanton-S
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 12.0
- Median LS (%)
- 15.0
- Mortality rate derease (%)
- —
- Max LS (%)
- 6.0
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0.005%
More info about experiment
Opposite effectNo