Valpromide

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CAS: 2430-27-5

Name:

Valpromide

Other names:

dipropylacetamide, depamide; 2-PROPYLPENTANAMIDE; 2-Ethylvaleramide; Pentanamide, 2-propyl-; Valpramide; 2-Propylpentamide; 2-Propylvaleramide

A derivative of Valproic acid (VPA) and is employed as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity.

Interactions

Description

UniProt ID

Protein: Epoxide hydrolase 1, Gene: EPHX1

Toxicity

oral LD50 [mouse] mg/kg
> 950.0
oral LD50 [rat] mg/kg
> 890.0
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Depressant
Anti Convulsant
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Data not available

Relation to aging associated genes

No data available

Experimental conditions

Agar nematode growth medium + E. coli OP50

Life Extension

Mean LS (%)
21.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
35.0
Cell CLS
Cell RLS

Concentration wth maximum effect

6 mM

More info about experiment

18248662
Opposite effectNo