Valpromide
CAS: 2430-27-5
Name:
Valpromide
Other names:
dipropylacetamide, depamide; 2-PROPYLPENTANAMIDE; 2-Ethylvaleramide; Pentanamide, 2-propyl-; Valpramide; 2-Propylpentamide; 2-Propylvaleramide
A derivative of Valproic acid (VPA) and is employed as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity.
Toxicity
- oral LD50 [mouse] mg/kg
- > 950.0
- oral LD50 [rat] mg/kg
- > 890.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Model organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
Agar nematode growth medium + E. coli OP50Life Extension
- Mean LS (%)
- 21.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- 35.0
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
6 mM
More info about experiment
Opposite effectNo