Tyrphostin 1
CAS: 2826-26-8
Name:
Tyrphostin 1
Other names:
Tyrphostin-1; Tyrphostin A1; (4-Methoxybenzylidene)malononitrile; 2-[(4-methoxyphenyl)methylidene]propanedinitrile
Tyrphostin A1 is part of the class of low molecular weight protein tyrosine kinase inhibitors. While a majority of Tyrphostins are tyrosine kinase blockers and are being researched as potential drugs for leukemias, cancers, psoriasis, as well as other proliferative conditions, Tyrphostin A1 is the inactive form. Tyrphostin A1 has usually been chosen as the negative control for Tyrphostin A23 and other Tyrphostin derivatives. [Santa Cruz Biotechnology].
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelDrosophila melanogaster
SrainOregon-R-C
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 19.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
100-300 mkM
More info about experiment
Opposite effectNo