Tyrphostin 1

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CAS: 2826-26-8

Name:

Tyrphostin 1

Other names:

Tyrphostin-1; Tyrphostin A1; (4-Methoxybenzylidene)malononitrile; 2-[(4-methoxyphenyl)methylidene]propanedinitrile

Tyrphostin A1 is part of the class of low molecular weight protein tyrosine kinase inhibitors. While a majority of Tyrphostins are tyrosine kinase blockers and are being researched as potential drugs for leukemias, cancers, psoriasis, as well as other proliferative conditions, Tyrphostin A1 is the inactive form. Tyrphostin A1 has usually been chosen as the negative control for Tyrphostin A23 and other Tyrphostin derivatives. [Santa Cruz Biotechnology].

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

No data
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Data not available

Relation to aging associated genes

No data available

Experimental conditions

Not available

Life Extension

Mean LS (%)
19.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

100-300 mkM

More info about experiment

22363408
Opposite effectNo