Tyrosol
CAS: 501-94-0
Name:
Tyrosol
Other names:
2-(4-Hydroxyphenyl)ethanol; Tyrosol; 4-(2-Hydroxyethyl)phenol; 4-(2-HYDROXYETHYL) PHENOL; Para Hydroxy Phenethyl Alcohol
Tyrosol is a phenolic compound present in two of the traditional components of the Mediterranean diet: wine and virgin olive oil. Tyrosol has been shown to be able to exert antioxidant activity in vitro studies. Oxidation of low-density lipoprotein (LDL) appears to occur predominantly in arterial intimae in microdomains sequestered from antioxidants of plasma. The antioxidant content of the LDL particle is critical for its protection. The ability of tyrosol to bind human LDL has been reported [HMDB].
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
No
No
No
Longevity mechanisms activation
Suppression of aging mechanisms
Relation to biomarkers of Aging
Antimicrobial activity of hydroxytyrosol, tyrosol, and oleuropein has been demonstrated against several strains of bacteria implicated in intestinal and respiratory infections. Although the majority of research has been conducted on the oil, consumption of whole olives might also confer health benefits
Relation to aging associated genes
No data available
Model organism
Experimental conditions
Agar nematode growth medium + E. coli OP50 25oCLife Extension
- Mean LS (%)
- 19.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- 10.8
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
250 mkM