Tyrosol

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CAS: 501-94-0

Name:

Tyrosol

Other names:

2-(4-Hydroxyphenyl)ethanol; Tyrosol; 4-(2-Hydroxyethyl)phenol; 4-(2-HYDROXYETHYL) PHENOL; Para Hydroxy Phenethyl Alcohol

Tyrosol is a phenolic compound present in two of the traditional components of the Mediterranean diet: wine and virgin olive oil. Tyrosol has been shown to be able to exert antioxidant activity in vitro studies. Oxidation of low-density lipoprotein (LDL) appears to occur predominantly in arterial intimae in microdomains sequestered from antioxidants of plasma. The antioxidant content of the LDL particle is critical for its protection. The ability of tyrosol to bind human LDL has been reported [HMDB].

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Neuroprotective
Cardioprotective
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

Stress Resistance

Suppression of aging mechanisms

Anti Oxidant

Relation to biomarkers of Aging

Antimicrobial activity of hydroxytyrosol, tyrosol, and oleuropein has been demonstrated against several strains of bacteria implicated in intestinal and respiratory infections. Although the majority of research has been conducted on the oil, consumption of whole olives might also confer health benefits

18069902 11905662

Relation to aging associated genes

No data available

Experimental conditions

Agar nematode growth medium + E. coli OP50 25oC

Life Extension

Mean LS (%)
19.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
10.8
Cell CLS
Cell RLS

Concentration wth maximum effect

250 mkM

More info about experiment

22824366
Opposite effectNo