Thioridazine Hydrochloride

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CAS: 130-61-0

Name:

Thioridazine Hydrochloride

Other names:

Thioridazine Hcl; Sonapax hydrochloride; Thioridazine chloride; Mellaril hydrochloride; USAF SZ-B

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618)

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
> 1060.0
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

No data
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

Stress Resistance
+

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Data not available

Relation to aging associated genes

No data available

Experimental conditions

S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50

Life Extension

Mean LS (%)
31.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

0,33%

More info about experiment

24134630
Opposite effectNo