Santokvin
CAS: 91-53-2
Name:
Santokvin
Other names:
Ethoxyquine; 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline; Santoquine; Niflex; Antioxidant EC; Santoflex A
Potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR).
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
Anti Oxidant
Relation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelMice
SrainC3H
Sex—
Age of treatment3 months
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 20.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
More info about experiment
Opposite effectNo
Model organism
ModelMice
SrainNZB
SexMale
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 32.1
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0.25%w (percent by weight)
More info about experiment
Opposite effectNo