Promethazine Hydrochloride

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CAS: 58-33-3

Name:

Promethazine Hydrochloride

Other names:

Phenergan; Promethazine Hcl; Fenergan; Atosil; Diprasine; Farganesse; Fellozine; Ganphen

A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals. [PubChem]

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
> 255.0
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Amiloid
Neuroprotective
Cardioprotective
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

Stress Resistance

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Increase in vertebral bone mineral content in postmenopausal women who are not taking oestrogen and greater increases in those who are

8340736

Relation to aging associated genes

No data available

Experimental conditions

S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50

Life Extension

Mean LS (%)
32.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

0.33%

More info about experiment

24134630
Opposite effectNo