Promethazine Hydrochloride
CAS: 58-33-3
Name:
Promethazine Hydrochloride
Other names:
Phenergan; Promethazine Hcl; Fenergan; Atosil; Diprasine; Farganesse; Fellozine; Ganphen
A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals. [PubChem]
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- > 255.0
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Suppression of aging mechanisms
No dataRelation to biomarkers of Aging
Increase in vertebral bone mineral content in postmenopausal women who are not taking oestrogen and greater increases in those who are
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 32.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0.33%
More info about experiment
Opposite effectNo