Oxaloacetic Acid
CAS: 328-42-7
Name:
Oxaloacetic Acid
Other names:
oxalacetic acid; 2-Oxobutanedioic acid; Ketosuccinic acid; 2-Oxosuccinic acid; Oxosuccinic acid; oxaloacetate; 2-Ketosuccinic acid
Oxaloacetic Acid substrate for malate dehydrogenase and oxaloacetate decarboxylase. Oxaloacetic Acid is an inhibitor of SDH.
Interactions
Description
UniProt ID
Protein: L-xylulose reductase, Gene: DCXR
Protein: Egl nine homolog 1, Gene: EGLN1
Protein: Egl nine homolog 2, Gene: EGLN2
Protein: Egl nine homolog 3, Gene: EGLN3
Protein: Thiosulfate sulfurtransferase, Gene: TST
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Calorie Restriction Mimetics
+
Suppression of aging mechanisms
No dataRelation to biomarkers of Aging
Human studies indicate a substantial reduction in fasting glucose levels and improvement in insulin resistance
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—