Nortriptyline Hydrochloride
CAS: 894-71-3
Name:
Nortriptyline Hydrochloride
Other names:
Nortriptyline hydrochloride; Pamelor; Allegron; Altilev; Nortrilen; Psychostyl; Acetexa; Sensival; Vividyl
Nortriptyline Hydrochloride is a 5-HT2 serotonin receptor antagonist. It is a more potent inhibitor of the norepinephrine transporter (Ki = 3.4 nM) than the serotonin transporter (Ki = 161 nM).
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- > 260.0
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 21.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,33%
More info about experiment
Opposite effectNo