Myricetin

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CAS: 529-44-2

Name:

Myricetin

Other names:

Cannabiscetin; Myricetol; Myricitin; 3,3',4',5,5',7-Hexahydroxyflavone

Myricetin is flavonol, consisting of 3-hydroxyflavone backbone and 6 hydroxyl groups. Pure myricetin is a yellow-beige powder crystalline powder. Myricetin mainly occurs in nature in the form of glycosides. Myricetin is found in several foods such as walnuts, onions, berries, herbs and red grapes. Myricetin exerts a wide variety of biological effects, including antioxidant and free radical-scavenging activities. Reports indicate that myricetin has anti-cancer and anti-inflammatory properties and may improve bone-health.

Interactions

Description

UniProt ID

Protein: Multidrug resistance-associated protein 1, Gene: ABCC1
Protein: Aryl hydrocarbon receptor, Gene: AHR
Protein: Aldose reductase, Gene: AKR1B1
Gene: CSNK2A1
Protein: Casein kinase II subunit alpha', Gene: CSNK2A2
Protein: Casein kinase II subunit beta, Gene: CSNK2B
Protein: Cyclin-dependent-like kinase 5, Gene: CDK5
Protein: Catechol O-methyltransferase, Gene: COMT
Protein: Cytochrome P450 1A2, Gene: CYP1A2
Protein: Inositol polyphosphate multikinase, Gene: IPMK
Protein: Inositol-trisphosphate 3-kinase A, Gene: ITPKA
Protein: Inositol-trisphosphate 3-kinase B, Gene: ITPKB
Protein: Inositol-trisphosphate 3-kinase C, Gene: ITPKC
Protein: Serine/threonine-protein kinase pim-1, Gene: PIM1
Protein: Serine/threonine-protein kinase PLK1, Gene: PLK1
Protein: DNA polymerase alpha catalytic subunit, Gene: POLA1
Protein: DNA polymerase alpha subunit B, Gene: POLA2
Protein: Sulfotransferase 1A1, Gene: SULT1A1
Protein: DNA topoisomerase 2-alpha, Gene: TOP2A
Protein: DNA topoisomerase 2-beta, Gene: TOP2B
Protein: Transthyretin, Gene: TTR
Protein: Protein kinase C alpha type, Gene: PRKCA
Protein: Protein kinase C beta type, Gene: PRKCB
Protein: Protein kinase C delta type, Gene: PRKCD
Protein: Protein kinase C epsilon type, Gene: PRKCE
Protein: Protein kinase C gamma type, Gene: PRKCG
Protein: Protein kinase C eta type, Gene: PRKCH
Protein: Protein kinase C iota type, Gene: PRKCI
Protein: Protein kinase C theta type, Gene: PRKCQ
Protein: Protein kinase C zeta type, Gene: PRKCZ
Protein: Serine/threonine-protein kinase D1, Gene: PRKD1
Gene: PRKD2
Protein: Serine/threonine-protein kinase D3, Gene: PRKD3
Protein: cAMP-dependent protein kinase catalytic subunit alpha, Gene: PRKACA
Gene: PRKACB
Protein: cAMP-dependent protein kinase catalytic subunit gamma, Gene: PRKACG
Protein: Myosin light chain kinase, smooth muscle, Gene: MYLK
Protein: Myosin light chain kinase 2, skeletal/cardiac muscle, Gene: MYLK2
Protein: Myosin light chain kinase 3, Gene: MYLK3
Gene: INSR
Gene: CSNK1A1
Protein: Casein kinase I isoform alpha-like, Gene: CSNK1A1L
Protein: Casein kinase I isoform delta, Gene: CSNK1D
Protein: Casein kinase I isoform epsilon, Gene: CSNK1E
Protein: Casein kinase I isoform gamma-1, Gene: CSNK1G1
Protein: Uncharacterized protein CSNK1G2-AS1, Gene: CSNK1G2-AS1
Protein: Casein kinase I isoform gamma-3, Gene: CSNK1G3

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Inflammation
Anti Cancer
Anti Amiloid
Neuroprotective
Cardioprotective
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

Anti Oxidant

Relation to biomarkers of Aging

Anti-aging agent for skin care

19778600

Relation to aging associated genes

POLA1PRKCAPRKCAPRKCDINSRTOP2ATOP2BCSNK1E

Experimental conditions

liquid medium + E. coli OP50

Life Extension

Mean LS (%)
32.9
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

10 mkM

More info about experiment

23736695
Opposite effectNo