Mianserin
CAS: 24219-97-4
Name:
Mianserin
Other names:
Mianserine; Mianserina; Mianserinum; Tolvon; Mianseryna [Polish]; Mianseryna; Norval; Mianserine [INN-French]
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favor of Mirtazapine.
Interactions
Description
UniProt ID
Protein: Muscarinic acetylcholine receptor, Gene: CHRM1
Protein: Muscarinic acetylcholine receptor, Gene: CHRM2
Protein: Muscarinic acetylcholine receptor M3, Gene: CHRM3
Protein: Muscarinic acetylcholine receptor M4, Gene: CHRM4
Protein: Muscarinic acetylcholine receptor M5, Gene: CHRM5
Protein: Alpha-1A adrenergic receptor, Gene: ADRA1A
Protein: Alpha-1B adrenergic receptor, Gene: ADRA1B
Protein: Alpha-1D adrenergic receptor, Gene: ADRA1D
Protein: Alpha-2A adrenergic receptor, Gene: ADRA2A
Protein: Alpha-2B adrenergic receptor, Gene: ADRA2B
Gene: ADRA2C
Protein: D(1A) dopamine receptor, Gene: DRD1
Protein: D(2) dopamine receptor, Gene: DRD2
Gene: DRD3
Protein: D(4) dopamine receptor, Gene: DRD4
Protein: Sodium-dependent dopamine transporter, Gene: SLC6A3
Protein: Sodium- and chloride-dependent GABA transporter 2, Gene: SLC6A13
Protein: ATP-dependent RNA helicase DHX8, Gene: DHX8
Protein: Histamine H2 receptor, Gene: HRH2
Protein: Histamine H3 receptor, Gene: HRH3
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- > 780.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Calorie Restriction Mimetics
+
Stress Resistance
+
Suppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—