Lamotrigine
CAS: 84057-84-1
Name:
Lamotrigine
Other names:
Lamictal; Lamictal Cd; Lamotrigina; Lamotriginum; Labileno; Lamictin; Lamiktal; Lamictal XR; Crisomet
Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. It is also used off-label as an adjunct in treating clinical depression.[1] For epilepsy, it is used to treat focal seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration (FDA)-approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I. [Wikipedia]
Interactions
Description
UniProt ID
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- > 185.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No
No
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 17.2
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- 17.6
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
12 mg/ml