Kaempferol
CAS: 520-18-3
Name:
Kaempferol
Other names:
Kempferol; Kaempherol; Populnetin; Rhamnolutein; Robigenin; Trifolitin; Pelargidenolon; Rhamnolutin; Swartziol
Kaempferol is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods. Kaempferol is a yellow crystalline solid with a melting point of 276–278 °C (529–532 °F). It is slightly soluble in water and highly soluble in hot ethanol, ethers, and DMSO. Kaempferol acts as an antioxidant by reducing oxidative stress. Many studies suggest that consuming kaempferol may reduce the risk of various cancers and kaempferol is currently under consideration as a possible cancer treatment [Wikipedia]
Interactions
Description
UniProt ID
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No
No
No
Longevity mechanisms activation
Suppression of aging mechanisms
Relation to biomarkers of Aging
Inhibits cancer cell growth and angiognesis and induces cancer cell apoptosis, but on the other hand, kaempferol appears to preserve normal cell viability, in some cases exerting a protective effect
Model organism
Experimental conditions
Agar nematode growth medium + E. coli OP50 37oC thermal stressLife Extension
- Mean LS (%)
- —
- Median LS (%)
- —
- Mortality rate derease (%)
- 10.0
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
100 mkM