Gallic Acid
CAS: 149-91-7
Name:
Gallic Acid
Other names:
3,4,5-Trihydroxybenzoic acid; Acid, Gallic; Benzoic acid; 3,4,5-trihydroxy-; D005707
Gallic acid is an antiinflammatory and Cox (cyclooxygease inhibitory substance found in plants and has been shown to Induce apoptosis in human lung cancer cells. It is cytotoxic to PC14 AND MKN45 human cancer cell lines.
Interactions
Description
UniProt ID
Protein: Matrix metalloproteinase-9, Gene: MMP9
Protein: Carbonic anhydrase 1, Gene: CA1
Protein: Carbonic anhydrase 2, Gene: CA2
Protein: Carbonic anhydrase 4, Gene: CA4
Protein: Carbonic anhydrase 9, Gene: CA9
Protein: Carbonic anhydrase 5A, mitochondrial, Gene: CA5A
Protein: Carbonic anhydrase 5B, mitochondrial, Gene: CA5B
Protein: L-xylulose reductase, Gene: DCXR
Protein: Pancreatic triacylglycerol lipase, Gene: PNLIP
Protein: Ras-related protein Rab-9A, Gene: RAB9A
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- > 5000.0
Effects on organism
Anti Cancer
Anti Amiloid
Anti Obesity
Anti Diabetic
Neuroprotective
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Suppression of aging mechanisms
Anti Oxidant
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
Agar nematode growth medium + E. coli OP50Life Extension
- Mean LS (%)
- 10.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
300 mkM
More info about experiment
Opposite effectNo