Ethylene-Diamine-Tetra-Acetic Acid

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CAS: 60-00-4

Name:

Ethylene-Diamine-Tetra-Acetic Acid

Other names:

EDTA; Ethylenediaminetetraacetic acid; Edathamil; Endrate; Havidote; Titriplex; Versenate; Versene

A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive. [PubChem]

Interactions

Description

UniProt ID

Protein: Zinc finger protein 40, Gene: HIVEP1

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Atherogenic
Cardioprotective
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

Metal Ion Chelating
Anti Oxidant

Relation to biomarkers of Aging

Benefits on arteriosclerosis

[Hancke C, Flytie K. Benefits of EDTA chelation therapy on arteriosclerosis. J Adv Med. 1993; 6:161-172.]; 8820322

Relation to aging associated genes

No data available

Experimental conditions

Not available

Life Extension

Mean LS (%)
50.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
25.0
Cell CLS
Cell RLS

Concentration wth maximum effect

More info about experiment

Komarov, L.V., and Bakaev, V.V. Means of the Life Prolongation, Rejuvenation, 1983, XI: 2-3, 46-51
Opposite effectNo