Doxycycline
CAS: 564-25-0
Name:
Doxycycline
Other names:
Doxycycline
A synthetic tetracycline derivative with similar antimicrobial activity. Animal studies suggest that it may cause less tooth staining than other tetracyclines. It is used in some areas for the treatment of chloroquine-resistant falciparum malaria (malaria, falciparum). [PubChem]
Interactions
Description
UniProt ID
Protein: Nuclear receptor subfamily 1 group I member 2, Gene: NR1I2
Gene: CYP3A4
Protein: Collagenase 3, Gene: MMP13
Protein: 72 kDa type IV collagenase, Gene: MMP2
Toxicity
- oral LD50 [mouse] mg/kg
- > 1900.0
- oral LD50 [rat] mg/kg
- > 0.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Anti Inflammation
Anti Cancer
Anti Amiloid
Anti Atherogenic
Anti Depressant
Cardioprotective
Antibacterial
S4005
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Suppression of aging mechanisms
Anti Oxidant
Relation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—