Dimebolin
CAS: 3613-73-8
Name:
Dimebolin
Other names:
Dimebolin; Dimebon; Dimeboline; Latrepirdine; Dimebone
Latrepirdine (INN, also known as dimebolin and sold as Dimebon), is an antihistamine drug which has been used clinically in Russia since 1983 [Wikipedia]
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataRelation to biomarkers of Aging
Stimulation of autophagy;Neuroprotective effect: Dimebone improved the clinical course of patients with mild-to-moderate Alzheimer's disease (in clinical trials phase II)
Relation to aging associated genes
No data available
Model organism
ModelMice
SrainC57BL/6
Sex—
Age of treatment8 month
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 2.5
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- 3.7
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
1.5 mg/kg/day
More info about experiment
Opposite effectNo