Warning! Toxic compound!

Carbonylcyanide-P-Trifluoromethoxyphenylhydrazone

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CAS: 370-86-5

Name:

Carbonylcyanide-P-Trifluoromethoxyphenylhydrazone

Other names:

FCCP; Carbonyl cyanide p-trifluoromethoxyphenylhydrazone; EINECS 206-730-8; BRN 4693268

Is an ionophore that is a mobile ion carrier. It referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation [Wiki]

Interactions

Description

UniProt ID

Protein: Solute carrier organic anion transporter family member 1B3, Gene: SLCO1B3

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

No data
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Data not available

Relation to aging associated genes

No data available

Experimental conditions

Agar nematode growth medium + E. coli OP50

Life Extension

Mean LS (%)
38.46
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

50 mkM

More info about experiment

18221415
Opposite effectNo