Butylated Hydroxytoluene
CAS: 128-37-0
Name:
Butylated Hydroxytoluene
Other names:
2,6-Di-tert-butyl-4-methylphenol; Butylhydroxytoluene; 2,6-Di-tert-butyl-p-cresol; Dibunol; Ionol; DBPC; BHT
Butylated hydroxytoluene (BHT) is an antioxidant shown to be chemopreventive against a variety of carcinogens.
Interactions
Description
UniProt ID
Protein: Calpain-1 catalytic subunit, Gene: CAPN1
Protein: Sortilin-related receptor, Gene: SORL1
Toxicity
- oral LD50 [mouse] mg/kg
- > 650.0
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Anti Amiloid
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Suppression of aging mechanisms
Anti Oxidant
Relation to biomarkers of Aging
Decrease in AF-DNA adduct formation was seen in the human colon tumor cells
Relation to aging associated genes
No data available
Model organism
ModelMice
SrainBALB/c
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 19.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- 23.0
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,75%
More info about experiment
Opposite effectNo