Brl 15572
CAS: 1173022-77-9
Name:
Brl 15572
Other names:
BRL 15572 hydrochloride is a selective SR-1D antagonist, displaying 60-fold selectivity over SR-1B, and exhibiting little or no affinity for a range of other receptor types.
Interactions
Description
UniProt ID
Protein: 5-hydroxytryptamine receptor 1E, Gene: HTR1E
Protein: 5-hydroxytryptamine receptor 6, Gene: HTR6
Protein: 5-hydroxytryptamine receptor 1B, Gene: HTR1B
Protein: 5-hydroxytryptamine receptor 1D, Gene: HTR1D
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 10.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,33%
More info about experiment
Opposite effectNo