Bezafibrate
CAS: 41859-67-0
Name:
Bezafibrate
Other names:
Bezalip; Cedur; Befizal; Bezafibrat; Bezatol; Bezalip Retard; durabezur; Bezafibrato
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Interactions
Description
UniProt ID
Protein: Peroxisome proliferator-activated receptor alpha, Gene: PPARA
Protein: Peroxisome proliferator-activated receptor delta, Gene: PPARD
Protein: Alkaline phosphatase, tissue-nonspecific isozyme, Gene: ALPL
Protein: Carnitine O-acetyltransferase, Gene: CRAT
Protein: Enoyl-CoA hydratase, mitochondrial, Gene: ECHS1
Protein: Aldose reductase, Gene: AKR1B1
Protein: Carboxylic ester hydrolase, Gene: CES2
Gene: SLCO1B1
Protein: Solute carrier family 22 member 6, Gene: SLC22A6
Protein: Glutathione peroxidase 1, Gene: GPX1
Protein: Glutathione reductase, mitochondrial, Gene: GSR
Toxicity
- oral LD50 [mouse] mg/kg
- > 732.0
- oral LD50 [rat] mg/kg
- > 1082.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Anti Inflammation
Anti Atherogenic
Anti Obesity
Cardioprotective
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataModel organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 12.96
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
10 mkM
More info about experiment
Opposite effectNo