Berberine
CAS: 2086-83-1
Name:
Berberine
Other names:
Berberin; Umbellatine; Majarine; Thalsine; Berberal; UNII-0I8Y3P32UF; EINECS 218-229-1
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- > 0.0
- oral LD50 [rat] mg/kg
- > 0.0
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Anti Inflammation
Anti Cancer
Anti Obesity
Anti Diabetic
Anti Depressant
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to aging associated genes
No data available
Model organism
ModelDrosophila melanogaster
SrainOregon-R-C
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 27.0
- Median LS (%)
- 57.0
- Mortality rate derease (%)
- —
- Max LS (%)
- 78.0
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
1 mM
More info about experiment
Opposite effectNo