Beauveriolide I
CAS: 154491-55-1
Name:
Beauveriolide I
Other names:
(3R,6S,9S,13S)-9-Benzyl-13-[(2S)-2-hexanyl]-3-isobutyl-6-methyl-1-oxa-4,7,10-triazacyclotridecane-2,5,8,11-tetrone
The depsipeptide from the fungal strain Beauveria sp. FO-6979. It has been shown that Beauveriolide I reduce atherogenic lesions in mouse models of atherosclerosis, and has potential ß-amyloid lowering activity [PMID:19396893]
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to aging associated genes
No data available
Model organism
ModelSaccharomyces cerevisiae
Srain—
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- —
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- 50.0
- Cell RLS
- —
Concentration wth maximum effect
20 mg/ml
More info about experiment
Opposite effectNo