Ascorbic Acid
CAS: 50-81-7
Name:
Ascorbic Acid
Other names:
l-ascorbic acid; vitamin C; ascorbate; Ascorbicap; Ascoltin; Cebione; Cevalin; Cecon; Cevex
L-Ascorbic Acid, Free Acid protects cells against the damaging effects of radiation and oxygen radicals. L-Ascorbic Acid increases the rate of mineralization in osteoblasts, is involved in hydroxylation of proline and lysine, reduces Na+/Ca2+exchange in cultured astrocytes and modulates cyclic nucleotide levels in B and T cells inhibits apoptosis in cultured rat ovarian follicles. Shown to inhibit T-type Ca++ CP α 1H.
Toxicity
- oral LD50 [mouse] mg/kg
- > 3367.0
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Suppression of aging mechanisms
Anti Oxidant
Relation to biomarkers of Aging
Enhances the expression of type 1 and type 4 collagen; Rationale for the use against cognitive decline; Expression of telomere-related genes
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
Not availableLife Extension
- Mean LS (%)
- 66.67
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
120 mkg
More info about experiment
Opposite effectNo