Ascorbic Acid

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CAS: 50-81-7

Name:

Ascorbic Acid

Other names:

l-ascorbic acid; vitamin C; ascorbate; Ascorbicap; Ascoltin; Cebione; Cevalin; Cecon; Cevex

L-Ascorbic Acid, Free Acid protects cells against the damaging effects of radiation and oxygen radicals. L-Ascorbic Acid increases the rate of mineralization in osteoblasts, is involved in hydroxylation of proline and lysine, reduces Na+/Ca2+exchange in cultured astrocytes and modulates cyclic nucleotide levels in B and T cells inhibits apoptosis in cultured rat ovarian follicles. Shown to inhibit T-type Ca++ CP α 1H.

Interactions

Description

UniProt ID

Protein: Solute carrier family 23 member 2, Gene: SLC23A2

Toxicity

oral LD50 [mouse] mg/kg
> 3367.0
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Anti Cancer
Neuroprotective
Cardioprotective
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

Stress Resistance

Suppression of aging mechanisms

Anti Oxidant

Relation to biomarkers of Aging

Enhances the expression of type 1 and type 4 collagen; Rationale for the use against cognitive decline; Expression of telomere-related genes

23228664 24763117 22843416

Relation to aging associated genes

No data available

Experimental conditions

Not available

Life Extension

Mean LS (%)
66.67
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

120 mkg

More info about experiment

19580823
Opposite effectNo