Amn082
CAS: 83027-13-8
Name:
Amn082
Other names:
AMN082; N,N'-Dibenzhydrylethane-1,2-diamine dihydrochloride; AMN082 DIHYDROCHLORIDE; SureCN3012657; CTK8F7746; AMN-082
AMN082 is a selective metabotropic glutamate receptor 7 (mGluR7) allosteric agonist. It mimics the effect of glutamate. AMN082 is the first selective mGluR7 agonist and has expanded the potential array of research opportunities on the effects of mGluR7 in the CNS.
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
Neuroprotective
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50Life Extension
- Mean LS (%)
- 8.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
0,33%
More info about experiment
Opposite effectNo