Warning! Toxic compound!

4-Phenyl-3-Furoxancarbonitrile

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CAS: 125520-62-9

Name:

4-Phenyl-3-Furoxancarbonitrile

Other names:

Furoxan; RVC-589; Furoxan, RVC-589; Lopac-P-1726; SureCN320190; Lopac0_000926; BSPBio_001187; KBioGR_000527

4-Phenyl-3-furoxancarbonitrile is able to activate GCS (soluble guanylate cyclase) by releasing nitric oxide with the aid of thiol cofactors. 4-Phenyl-3-furoxancarbonitrile has also been shown to inhibit platelet aggregation.

Interactions

No targets available

Toxicity

oral LD50 [mouse] mg/kg
Unavailable
oral LD50 [rat] mg/kg
Unavailable
oral LD50 [rabbit] mg/kg
Unavailable

Effects on organism

Cardioprotective
Antibacterial

No

Antifungal

No

Antiviral

No

Longevity mechanisms activation

No data

Suppression of aging mechanisms

No data

Relation to biomarkers of Aging

Data not available

Relation to aging associated genes

No data available

Experimental conditions

S-complete media in wells of 96 well + E. coli OP50plates containing E. coli OP50

Life Extension

Mean LS (%)
30.0
Median LS (%)
Mortality rate derease (%)
Max LS (%)
Cell CLS
Cell RLS

Concentration wth maximum effect

0,33%

More info about experiment

24134630
Opposite effectNo