7-Amino-1,2,4-Triazolo- [1,5-A]Pyridine-6,8-Dicarbonitriles
CAS: 274-85-1
Note
"This compound has ambiguous names, uses and effects in the literature. Additional verification is in progress and expanded literature review is advised."
Name:
7-Amino-1,2,4-Triazolo- [1,5-A]Pyridine-6,8-Dicarbonitriles
Other names:
7-amino-1,2,4-triazolo- [1,5-a]pyridine-6,8-dicarbonitriles
Presumedly enhanced expression of antioxidant genes like superoxide dismutase, catalase, and others, influences mitochondrial
Interactions
No targets available
Toxicity
- oral LD50 [mouse] mg/kg
- > 300.0
- oral LD50 [rat] mg/kg
- > 980.0
- oral LD50 [rabbit] mg/kg
- > 3200.0
Effects on organism
Anti Cancer
Antibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
Stress Resistance
Relation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabiditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
Agar nematode growth medium + E. coli OP50Life Extension
- Mean LS (%)
- 19.0
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
1 mkM
More info about experiment
Opposite effectNo